中文名稱    表皮生長因子樣蛋白6抗體    

英文名稱    EGFL6

別    名    EGF like domain multiple 6; EGF repeat containing protein 6; EGF-like protein 6; EGF-like-domain multiple 6; egfl6; EGFL6_HUMAN; epidermal growth factor like protein 6; Epidermal growth factor-like protein 6; MAEG; MAM and EGF domain containing; MAM and EGF domains containing gene protein; MAM and EGF domains-containing gene protein; W80.    

供 應(yīng) 商    遠慕生物         

研究領(lǐng)域    腫瘤  細胞生物  神經(jīng)生物學(xué)  生長因子和激素  細胞粘附分子      

抗體來源    Rabbit    

克隆類型    Polyclonal    

交叉反應(yīng)    Human, Mouse, Rat, Dog, Cow, Horse, Sheep,     

產(chǎn)品應(yīng)用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 表皮生長因子樣蛋白6抗體（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    59kDa    

細胞定位    細胞膜 細胞外基質(zhì) 分泌型蛋白     

性    狀    Lyophilized or Liquid    

濃    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human EGFL6    

亞    型    IgG    

純化方法    affinity purified by Protein A    

儲 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存條件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

表皮生長因子樣蛋白6抗體產(chǎn)品介紹    background:

This gene encodes a member of the epidermal growth factor(EGF) repeat superfamily. Members of this superfamily arecharacterized by the presence of EGF-like repeats and are ofteninvolved in the regulation of cell cycle, proliferation, anddevelopmental processes. The gene product contains a signalpeptide, suggesting that it is secreted; an EGF repeat regionconsisting of 4 complete EGF-like repeats and 1 partial EGF-likerepeat, 3 of which have a calcium-binding consensus sequence; anarg-gly-asp integrin association motif; and a MAM domain, which isbelieved to have an adhesive function. This gene is expressed earlyduring development, and its expression has been detected in lungand meningioma tumors. [provided by RefSeq, Jul 2008].

Function:
May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly.

Subcellular Location:
Secreted, extracellular space, extracellularmatrix, basement membrane (By similarity).

Similarity:
Belongs to the nephronectin family.
Contains 5 EGF-like domains.
Contains 1 MAM domain.

Database links:
UniProtKB/Swiss-Prot: Q8IUX8.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.