中文名稱    烯酰輔酶/A水合酶含結(jié)構(gòu)域蛋白2抗體    

英文名稱    ECHDC2  

別    名    1300017C12Rik; 2610009M20Rik; D4Ertd765e; Enoyl Coenzyme A hydratase domain containing 2; FLJ10948; Enoyl-CoA hydratase domain-containing protein 2; RGD1308525; RP23-379K6.3; ECHD2_HUMAN.    

供 應(yīng) 商    遠(yuǎn)慕生物     

研究領(lǐng)域    腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  新陳代謝      

抗體來源    Rabbit    

克隆類型    Polyclonal    

交叉反應(yīng)    Human, Mouse, Rat, Pig, Cow, Horse, Zebrafish, Sheep,     

產(chǎn)品應(yīng)用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 烯酰輔酶/A水合酶含結(jié)構(gòu)域蛋白2抗體（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    27kDa    

細(xì)胞定位    細(xì)胞漿     

性    狀    Lyophilized or Liquid    

濃    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human ECHDC2    

亞    型    IgG    

純化方法    affinity purified by Protein A    

儲 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存條件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

烯酰輔酶/A水合酶含結(jié)構(gòu)域蛋白2抗體產(chǎn)品介紹    background:

ECHDC2 is a 292 amino acid mitochondrial protein that exists as two isoforms which are produced by alternative splicing events. The gene encoding ECHDC2 maps to chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 encodes a large number of disease-associated proteins, including Lamin A which, when expressed abnormally, can build up in the nucleus and cause nuclear blebs, a characteristic of the rare aging disease Hutchinson-Gilford progeria. Additionally, genes that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinsons Disease, Gaucher disease, schizophrenia and Usher syndrome are all located on chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Function:
ECHDC2 belongs to the enoyl-CoA hydratase/isomerase family. There are two named isforms.

Subcellular Location:
Mitochondrion (Potential).

Similarity:
Belongs to the enoyl-CoA hydratase/isomerase family.

Database links:
UniProtKB/Swiss-Prot: Q86YB7.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.