英文名稱    DNER   

中文名稱    腦表皮生長因子跨膜蛋白DNER抗體   

別    名    Brain EGF repeat-containing transmembrane protein; Bret; Delta and Notch-like epidermal growth factor-related receptor; Delta/notch-like EGF-related receptor; Dner; DNER_HUMAN; PRO299; Transmembrane protein Bet; UNQ26.   

供應(yīng)商     遠(yuǎn)慕生物  

研究領(lǐng)域    神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  干細(xì)胞  細(xì)胞表面分子     

抗體來源    Rabbit   

克隆類型    Polyclonal   

交叉反應(yīng)    Human, Mouse, Rat, Dog, Cow, Sheep,    

產(chǎn)品應(yīng)用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 腦表皮生長因子跨膜蛋白DNER抗體（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.   

分 子 量    75kDa   

細(xì)胞定位    細(xì)胞漿 細(xì)胞膜    

性    狀    Lyophilized or Liquid   

濃    度    1mg/1ml   

免 疫 原    KLH conjugated synthetic peptide derived from human DNER   

亞    型    IgG   

純化方法    affinity purified by Protein A   

儲 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4   

保存條件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.   

腦表皮生長因子跨膜蛋白DNER抗體產(chǎn)品介紹    background:

Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.

Function:
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity).

Subunit:
Interacts with AP1G1. Interacts with NOTCH1 (By similarity).

Subcellular Location:
Cell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region.

Tissue Specificity:
Expressed in brain, spinal cord and adrenal gland.

Similarity:
Contains 10 EGF-like domains.
Contains 1 follistatin-like domain.

Database links:
UniProtKB/Swiss-Prot: Q8NFT8.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.