產(chǎn)品名稱：視網(wǎng)膜短鏈脫氫酶/還原酶家族7抗體

濃度：1mg/1ml

規(guī)格：0.2ml/200μg         

抗體來(lái)源：Rabbit 

克隆類型：polyclonal

交叉反應(yīng)：Human, Mouse, Rat, Rabbit  

產(chǎn)品類型：視網(wǎng)膜短鏈脫氫酶/還原酶家族7抗體一抗   

研究領(lǐng)域：細(xì)胞生物 免疫學(xué) 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 

蛋白分子量：predicted molecular weight: 35kDa

性狀：Lyophilized or Liquid

免疫原：KLH conjugated synthetic peptide derived from human DHRS7

亞型：IgG

純化方法：affinity purified by Protein A

儲(chǔ)存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

產(chǎn)品應(yīng)用：WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user. 

保存條件：Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

產(chǎn)品介紹：DHRS7 (dehydrogenase/reductase (SDR family) member 7), also known as SDR34C1, CGI-86 or retSDR4, is a 339 amino acid member of the SDR family. Like other members of the SDR family, DHRS7 contains a cofactor-binding Rossman-fold domain and is thought to catalyze the oxidation and reduction of a variety of substrates such as steroids and retinoids. DHRS7 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Similarity : Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Database links : UniProtKB/Swiss-Prot: Q9Y394.1