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產(chǎn)品名:短鏈脫氫還原酶13抗體
別名:Dehydrogenase/reductase (SDR family) member 13; Dehydrogenase/reductase SDR family member 13; DHRS 13; MGC23280; OTTHUMP00000163522; SDR7C5; Short chain dehydrogenase/reductase family 7C member 5; DHR13_HUMAN.
濃度:1mg/1ml
規(guī)格:0.2ml/200μg
抗體來源:Rabbit
克隆類型:polyclonal
交叉反應(yīng):Human, Mouse, Rat, Cow, Horse, Sheep
產(chǎn)品類型:短鏈脫氫還原酶13抗體一抗
研究領(lǐng)域:細(xì)胞生物 免疫學(xué) 發(fā)育生物學(xué) 神經(jīng)生物學(xué)
蛋白分子量:predicted molecular weight: 38kDa
性狀:Lyophilized or Liquid
免疫原:KLH conjugated synthetic peptide derived from human DHRS13
亞型:IgG
純化方法:affinity purified by Protein A
儲存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用:WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
保存條件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹:DHRS13 (dehydrogenase/reductase SDR family member 13), also known as UNQ419/PRO853, is a 377 amino acid secreted protein belonging to the short-chain dehydrogenases/reductases (SDR) family. DHRS13 is presumed to function as an oxidoreductase and is phosphorylated, potentially by ATM or ATR, upon DNA damage. DHRS13 exists as two isoforms produced by alternative splicing events. The gene encoding DHRS13 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Neurofibromatosis, dysregulated Schwann cell growth, Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are associated with chromosome 17.
Function : Putative oxidoreductase (Potential).
Subcellular Location : Secreted (Potential).
Post-translational modifications : Phosphorylated upon DNA damage, probably by ATM or ATR (By similarity).
Similarity : Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Database links : UniProtKB/Swiss-Prot: Q6UX07.1
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