英文名稱    DGCR2   
中文名稱    DGCR2蛋白抗體   
別    名    DGS C; DGS2; DiGeorge syndrome critical region gene 2; IDD; integral membrane protein DGCR2; LAN; SEZ 12.   
說 明 書    0.1ml  0.2ml     
研究領(lǐng)域    心血管  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)     
抗體來源    Rabbit   
克隆類型    Polyclonal   
交叉反應(yīng)    Human, Mouse, Rat, Cow, Rabbit, Zebrafish, xenopuslaevisorangutan   
產(chǎn)品應(yīng)用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500DGCR2蛋白抗體 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.   
分 子 量    59kDa   
細(xì)胞定位    細(xì)胞膜    
性    狀    Lyophilized or Liquid   
濃    度    1mg/1ml   
免 疫 原    KLH conjugated synthetic peptide derived from human DGCR2   
亞    型    IgG   
純化方法    affinity purified by Protein A   
儲 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4   
保存條件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.     
PubMed    PubMed   

DGCR2蛋白抗體產(chǎn)品介紹    background:
The DGCR2 gene encodes a novel putative adhesion receptor protein, which may play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22.

Function:
Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration.
Subcellular Location:
Membrane; Single pass type I membrane protein.
Tissue Specificity:
Predominantly expressed in brain, heart, lung and fetal kidney. Low levels in liver and adult kidney.

Similarity:
Contains 1 C-type lectin domain.
Contains 1 LDL-receptor class A domain.
Contains 1 VWFC domain.
Database links:
UniProtKB/Swiss-Prot: P98153.1