血清淀粉樣蛋白SAA抗體
其它名稱：SAA抗體，SAA antibody
貨號：grSA1-02
種類：抗體
應用：CILA，POCT，LETIA
特異性：Human SAA
來源：Mouse
存貯：-20℃
Mouse anti human SAA antibody
Serum amyloid A (SAA) is a family of proteins produced in the liver which are elevated in an acute-phase response. SAA3 is a member of this family that can be produced extrahepatically in inflammatory tissue by macrophages.109 SAA depositions are found in the granulomas in sarcoidosis patients.110 Elevated levels of serum SAA have been found in sarcoidosis,110,111 and higher levels were shown in patients with more active disease.39 Furthermore, data exist showing that serum SAA levels correlate with severity of lung function impairment and need for systemic therapy
產(chǎn)品說明
SAA通常與脂蛋白復合物存在，不同種類的SAA有不同的異構體，其數(shù)量各不相同SAA代表了哺乳動物中最保守的蛋白質之一，支持它在先天免疫系統(tǒng)中具有基本和必要作用的前提。在具有CRP的物種中，SAA通常反映了反應的大小和時間過程研究表明SAA在白細胞趨化和誘導額外的促炎細胞因子方面具有活性。此外，SAA還能誘導細胞外基質降解酶，幫助組織修復。
注意事項：
1.本品為蛋白質制劑，未添加任何防腐劑和保護劑，在2-8℃可短期保存
2.本品作為診斷試劑原輔材料，不得直接用于診斷或治療。
