產(chǎn)品新聞
背景資料
Troponin I (TnI), troponin T (TnT) and troponin C (TnC) form the troponin complex of the thin filaments of striated muscle. TnI is acts as the inhibitory subunit by blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains 3 genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TNNI3 gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in the TNNI3 gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
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來源宿主
大腸桿菌中重組表達
溶解建議
Sterile Filtered colorless liquid formulation. TNI solution containing 6M Urea 50mM Tris PH 8.
保存建議
TNI although stable at room temperature for 3 weeks, should be stored desiccated below -18℃. Upon reconstitution TNI should be stored at 4℃ between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
其他
ProSpec 是一家全球著名細胞因子蛋白生產(chǎn)和研發(fā)的公司,具有20多年的生產(chǎn)經(jīng)驗,專注于蛋白(重組及合成)生產(chǎn)研發(fā)。我們的核心產(chǎn)品包括:干擾素、白介素、骨蛋白、腫瘤壞死因子、成纖維生長因子、瘦素、干細胞因子、催乳素、表皮生長因子、胰島素樣生長因子、神經(jīng)生長因子、集落刺激因子、激素、酶、病毒抗原以及各種重組蛋白等。 生產(chǎn)工藝和規(guī)模使其可以提供毫克到克級蛋白,價格優(yōu)于同類公司。絕大部分產(chǎn)品是天然成熟型蛋白,而不含有標簽蛋白??紤]到大部分研究者希望能更靈活地配制蛋白溶液,ProSpec-Tany絕大部分產(chǎn)品沒有添加保護劑或鹽,這就對工藝提出了更高的要求。同時,ProSpec-Tany絕大部分產(chǎn)品為凍干粉,因此易于運輸和保存。