檢測Anti-AGER抗體,晚期糖基化終末產(chǎn)物特異性受體抗體

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檢測Anti-AGER抗體,晚期糖基化終末產(chǎn)物特異性受體抗體，可用于免疫組化（IHC），免疫印跡（WB），酶聯(lián)免疫（ELISA），IF、IP、流式細胞術等實驗（可來電索取說明）?。?/p>

詳細介紹

本公司，是專業(yè)經(jīng)營生物試劑，抗體，細胞，標準品，對照品的公司，在廣大用戶的幫助和支持下，經(jīng)過不懈的努力，已成為國內(nèi)生命科學領域產(chǎn)品的主要供應商之一，代理許多*水平的高科技產(chǎn)品，包括分子生物學、細胞生物學、免疫學、診斷等多個研究及應用領域。公司的服務和業(yè)務網(wǎng)絡遍及全國，在同行獲得*好評。

檢測Anti-AGER抗體,晚期糖基化終末產(chǎn)物特異性受體抗體簡單介紹：

產(chǎn)品別名：Advanced glycosylation end product specific receptor; Advanced glycosylation end product-specific receptor; AGER; EC 2.7.11.22; LE 9211 A antigen;LE-9211-A antigen; MGC22357; MOK; RAGE 1; RAGE1; MOK protein kinase; Receptor for advanced glycation endproducts;Renal tumor antigen 1; Renal tumor antigen; Renal cell carcinoma antigen (MOK protein kinase); Renal tumor antigen 1; RAGE_HUMAN.

產(chǎn)品用途：科研實驗

產(chǎn)品編號：BYK-0177R

性狀：Lyophilized or Liquid

濃度：1mg/1ml

亞型：IgG

貯存：貯存于-20℃.

此抗體本公司有單抗和多抗，可用于免疫組化（IHC），免疫印跡（WB），酶聯(lián)免疫(ELISA)，IF、IP、流式細胞術等實驗（可來電索取說明）

相關標記有：Alexa Fluor 350 標記、Alexa Fluor 488 標記、Alexa Fluor 555 標記、Alexa Fluor 647 標記、AP標記、APC標記、Biotin標記、Cy3標記、Cy5標記、Cy5.5標記、Cy7標記、FITC標記、Gold標記、HRP標記、PE標記、PE-Cy3標記、PE-CY5標記、PE-CY5.5標記、PE-CY7標記、RBITC標記

檢測Anti-AGER抗體,晚期糖基化終末產(chǎn)物特異性受體抗體產(chǎn)品說明：Advanced glycosylation end product-specific receptor (AGER; RAGE) is a member of the immunoglobulin superfamily of cell surface molecules that binds molecules that have been irreversibly modified by non-enzymatic glycation and oxidation, and are know as advanced glycation end products (AGEs). It is expressed by endothelium, mononuclear phagocytes, neurons and smooth muscle cells. Whereas RAGE is present at high levels during development, especially in the central nervous system, its levels decline during maturity.The increased expression of RAGE is associated with several pathological states, such as diabetic vasculopathy, neuropathy, retinopathy and other disorders, including Alzheimer's disease and immune/inflammatory reactions of the vessel walls. In diabetic tissues, the production of RAGE is due to the overproduction of AGEs that eventually overwhelm the protective properties of RAGE. This results in oxidative stress and endothelial cell dysfunction that leads to vascular disease in diabetics. In the brain, RAGE also binds amyloid beta (Ab). Because Ab is overproduced in neurons and vessels in the brains of Alzheimer disease, this leads to the hyperstimulation of RAGE. The RAGE-Ab interaction is thought to result in oxidative stress leading to neuronal degeneration.

保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
連續(xù)使用時4°C存儲，保質(zhì)期六個月補體C1qα鏈多肽抗體*存儲時建議分裝為10ul以上小包裝-20°C存儲，并避免反復凍融，保質(zhì)期一年。

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