Anti-Caspase-10抗體,優(yōu)質(zhì)半胱胺酸蛋白酶10抗體

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【產(chǎn)品名稱】：Anti-Caspase-10抗體,優(yōu)質(zhì)半胱胺酸蛋白酶10抗體

【產(chǎn)品編號】：BYK-0092R

【產(chǎn)品規(guī)格】：0.1ml/0.2ml

【產(chǎn)品價格】：詢價（電詢或客服）

【抗體來源】：Rabbit OR Mouse or Goat

【產(chǎn)品用途】：科研實驗，用于ELISA實驗、免疫組化實驗，WB實驗，IF實驗等，可，索取產(chǎn)品說明書！
【性狀】： Lyophilized or Liquid
【濃度】： 1mg/1ml
【亞型】： IgG

【貯存】：貯存于-20℃.

【相關(guān)標記】：HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647

【產(chǎn)品別名】：ALPS 2; ALPS2; Apoptosis related cysteine peptidase; Apoptotic protease Mch 4; CASP 10; CASP10; CASP10 protein; Caspase 10 apoptosis related cysteine peptidase; Caspase 10 apoptosis related cysteine protease; Caspase10; FADD Like Ice 2; Fas Associated Death Domain Protein; FAS associated death domain protein interleukin 1B converting enzyme 2; FLICE 2; FLICE2; ICE Like Apoptotic Protease 4; Interleukin 1B Converting Enzyme 2; MCH 4; MCH4.

【產(chǎn)品介紹】：Caspases are a family of intracellular proteases that mediate cell death and are the principal effectors of apoptosis. Caspase 10 (Mch4, ICE-LAP4, FLICE2) plays an important role in apoptosis induced by a variety of inducers such as TNF alpha and Anti-Fas antibody. It is a large prodomain caspase classified together with caspases 2, 8, and 9 as a signaling caspase. Four isoforms of caspase 10 (caspase 10a, 10b, 10c, and 10d) having the same prodomain but different mature large and small subdomain, have been described. Caspase 10 contains two death domains (DED) involved in linking to the death effector domain of the adapter protein FADD and recruiting the complex to TNFR1 and Fas. The inactive procaspase 10 is variably expressed in many tissues and cell lines as a cytosolic protein. The mature form of caspase 10 comprises two subunits, p23/p17 (splice isoforms) and p12. Interestingly, a caspase 9- dependent processing of caspase 10 by caspase 6 in cell-free extracts has recently been suggested. Caspase 10 can cleave and activate caspases 3, 4, 6, 7, 8, and 9. This is followed by cleavage of numerous key proteins, including the nuclear protein PARP.

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