Anti-Ubiquitin抗體,泛素蛋白抗體Background: Ubiquitin is a highly conserved protein, which has an ATP dependent role in the targeting of proteins for proteolytic degradation. To perform this function, the protein to be degraded is first covalently attached to the C terminus of ubiquitin, and the ubiquitinated complex is then recognized by a complex of degradative enzymes. Interestingly, ubiquitin also becomes covalently bonded to many types of pathological inclusions, which appear to be resistant to normal degradation. Therefore, ubiquitin antibodies are very useful for studies of these inclusions. For example, the neurofibrillary tangles and paired helical filaments diagnostic of Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease are all heavily ubiquitinated and can be readily visualized with ubiquitin antibodies
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Anti-Ubiquitin抗體,泛素蛋白抗體相關(guān)產(chǎn)品：
Anti-ChRM2 (Muscarinic Acetylcholine receptor M2) 毒蕈堿型乙酰*受體抗體
Anti-ChRM1 (Muscarinic Acetylcholine receptor M1) 毒蕈堿型乙酰*受體M1抗體
Anti-ChRM2 (Muscarinic Acetylcholine receptor M2) 毒蕈堿型乙酰*受體M2抗體
Anti-ChRM3 (Muscarinic Acetylcholine receptor M3) 毒蕈堿型乙酰*受體M3抗體
Anti-CIDE-B/DFF45(Cell death-inducing DFF45-like effector-B) 促進(jìn)凋亡基因抗體
anti-CIB1(Calcium and integrin binding 1) 鈣-整合素結(jié)合蛋白1抗體
Anti-C-jun/AP-1/JUN 原癌基因蛋白/活化蛋白1抗體
Anti-phospho-c-Jun/AP-1(pThr91+pThr93) 抗磷酸化原癌基因c-Jun抗體
Anti-Jun B 活化蛋白激酶B抗體
Anti-Jun D 活化蛋白激酶D抗體
Anti-CKⅠα/STK（Casein kinase Ⅰα/Serine/Threonine Protein KinaseⅠα/） 屬絲/*蛋白質(zhì)激酶抗體
Anti-CKⅡα/STK（Casein kinase Ⅱα;Serine/Threonine Protein KinaseⅡα） 屬絲/*蛋白質(zhì)激酶抗體
Anti-CKⅡα/STK(Casein kinase Ⅱα;Serine/Threonine Protein KinaseⅡα) 屬絲/*蛋白質(zhì)激酶抗體
Anti-P-CK（pan-cytokeratin） 廣譜細(xì)胞角蛋白抗體
Anti-CK18（Cytokeratin 18） 細(xì)胞角蛋白18抗體
Anti-Ubiquitin抗體,泛素蛋白抗體Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation and may be required for numerous functions, including maintenance of chromatin structure, regulation of gene expression, stress response, ribosome biogenesis and DNA repair
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