Anti-Factor X抗體,*10抗體說明書
Catalog Number : BYK-9501R
Quantity size : 0.1ml （dilute with pH 7.4 0.01 M PBS or antibody diluent ）
Background: Hemostasis following tissue injury involves the deployment of essential plasma procoagulants （Prothrombin and Factors X, IX, V and VIII）, which are involved in a blood coagulation cascade that leads to the formation of insoluble Fibrin clots and the promotion of plaet aggregation. Coagulation Factor X （Stuart Prower factor, FX, F10） is a vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor. The mature form of Factor X （Factor X A） is generated by Factor IX A- or Factor VII A-mediated cleavage at the tripeptide sequence, Arg-Lys-Arg, to yield a disulfide linked dimer. Together with the cofactor Factor V A and Ca2+ on the surface of plaets or endothelial cells, Factor X A coordinates as part of the prothrombinase complex, which mediates proteolysis of Prothrombin into active Thrombin. Mutations at the Factor X locus resulting in Factor X deficiencies can contribute to hemorrhagic diathesis.
Specificity :
–Anti-Factor Xis a mouse polyclonal antibody unconjugated
–specific for Factor X of Human, Mouse, Rat
–use for western blotting,elisa,immunoprecipitation and immunohistochemistry
–Protein G affinity chromatography purification, purity :>95%
–Isotype: IgG
–mol wt: 55kDa
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Anti-Factor X抗體,*10抗體說明書Application :
–Western blotting 1:100-500
–Immunohistochemistry 1:100-500
–ELISA 1:500-1000 IF=1:50-200
–KLH conjugated synthetic peptide derived from hu Factor X,
–Optimal working dilutions must be determined by the end user.
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Anti-Factor X抗體,*10抗體說明書Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
