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Anti-MBP抗體說明書,髓鞘堿性蛋白抗體技術(shù)交流

閱讀:368發(fā)布時(shí)間:2013-1-16

  Anti-MBP抗體說明書,髓鞘堿性蛋白抗體技術(shù)交流
  
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  MOUSEAnti-MBPantibody
  
  CatalogNumber:BYK-0380R
  
  Quantitysize:0.1ml(dilutewithpH7.40.01MPBSorantibodydiluent)
  
  Background:TheclassicgroupofMyelinbasicprotein(MBP)isoforms(isoforms4to14)arewithPLPthemostabundantproteincomponentsofthemyelinmembraneintheCNS.Theyhavearoleinbothitsformationandstabilization.Thesmallerisoformsmighthaveanimportantroleinremyelinationofdenudedaxonsinmultiplesclerosis.ThenonclassicgroupofMBPisoforms(isoforms1to3/GolliMBPs)maypreferentiallyhavearoleintheearlydevelopingbrainlongbeforemyelination,maybeascomponentsoftranscriptionalcomplexes,andmayalsobeinvolvedinsignalingpathwaysinTcellsandneuralcells.Differentialsplicingeventscombinedtooptionalposttranslationalmodificationsgiveawidespectrumofisomers,eachofthemhavingmaybeaspecializedfunction.
  
  Specificity:
  
  –Anti-MBPisamousemonoclonalantibodyunconjugated
  
  –specificforMBPofHuman,Mouse,Rat,Goat,Rabbit,Sheep
  
  –useforwesternblotting,elisa,immunoprecipitationandimmunohistochemistry
  
  –ProteinGaffinitychromatographypurification,purity:>95%
  
  –Isotype:IgG
  
  –molwt:33kDa
  
  Anti-MBP抗體說明書,髓鞘堿性蛋白抗體技術(shù)交流
  
  Application:
  
  –Westernblotting1:100-500
  
  –Immunohistochemistry1:100-500
  
  –ELISA1:500-1000
  
  –Optimalworkingdilutionsmustbedeterminedbytheenduser.
  
  Storage:Storeat-20℃foroneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20℃.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibody,theantibodyisstableforatleastsixweeksat2-4℃
  
  Anti-MBP抗體說明書,髓鞘堿性蛋白抗體技術(shù)交流
  
  ImportantNote:Thisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplications.

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