標(biāo)簽：延伸因子EF-1δ抗體 古朵生物 抗原抗體

　　古朵闡述：延伸因子EF-1δ抗體應(yīng)用方法

　　中文名稱 延伸因子EF-1δ抗體

　　英文名稱 EEF1D

　　別 名 Antigen NY CO 4; Antigen NY-CO-4; EEF 1D; EEF1D; EF 1 delta; EF 1D; EF-1-delta; EF1D; EF1D_HUMAN; Elongation factor 1 delta; Elongation factor 1-delta; Eukaryotic translation elongation factor 1 delta; Guanine nucleotide exchange protein.

　　研究領(lǐng)域 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 轉(zhuǎn)運(yùn)蛋白 表觀遺傳學(xué)

　　抗體來(lái)源 Rabbit

　　克隆類型 Polyclonal

　　交叉反應(yīng) Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep,

　　產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 延伸因子EF-1δ抗體(石蠟切片需做抗原修復(fù))

　　not yet tested in other applications.

　　optimal dilutions/concentrations should be determined by the end user.

　　分 子 量 31kDa

　　性 狀 Lyophilized or Liquid

　　濃 度 1mg/1ml

　　免 疫 原 KLH conjugated synthetic peptide derived from human EEF1D

　　亞 型 IgG

　　純化方法 affinity purified by Protein A

　　儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

　　保存條件 Store at -20 亱C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20亱C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 亱C.

　　延伸因子EF-1δ抗體產(chǎn)品介紹 background:

　　This gene encodes a subunit of the elongation factor-1complex, which is responsible for the enzymatic delivery ofaminoacyl tRNAs to the ribosome. This subunit, delta, functions asguanine nucleotide exchange factor. It is reported that followingHIV-1 infection, this subunit interacts with HIV-1 Tat. Thisinteraction results in repression of translation of host cellproteins and enhanced translation of viral proteins. Severalalternatively spliced transcript variants encoding multipleisoforms have been found for this gene. Related pseudogenes havebeen defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided byRefSeq, Aug 2010].

　　Function:

　　EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

　　Subunit:

　　EF-1 is composed of 4 subunits: alpha, beta, deltaisoform 1, and gamma. Isoform 2 interacts with HSF1 and NFE2L2.

　　Subcellular Location:

　　Isoform 2: Nucleus.

　　Tissue Specificity:

　　Isoform 2 is specifically expressed in brain,cerebellum and testis.

　　Post-translational modifications:

　　Phosphorylated upon DNA damage, probably by ATM or ATR.

　　Similarity:

　　Belongs to the EF-1-beta/EF-1-delta family.

　　Database links:

　　UniProtKB/Swiss-Prot: P29692.5

　　Important Note:

　　This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

　　古朵闡述：延伸因子EF-1δ抗體應(yīng)用方法 古朵一直視質(zhì)量控制為企業(yè)的生命，追求企業(yè)競(jìng)爭(zhēng)力的不斷提升。公司始終秉承信譽(yù)為生存之本的宗旨，以過(guò)硬的質(zhì)量和優(yōu)良的服務(wù)來(lái)維護(hù)和拓展市場(chǎng)，較大限度的滿足客戶的需求。與客戶的共贏，是我們的發(fā)展目標(biāo)。古朵!您信任的合作伙伴。我們?cè)概c您真誠(chéng)合作，共創(chuàng)美好的未來(lái)。