Rho GTP酶激活蛋白15抗體供應(yīng)
『別名』ArhGAP15; BM046; Rho GTPase activating protein 15; Rho type GTPase activating protein 15; RHG15_HUMAN.
『濃度』1mg/1ml
『規(guī)格』0.2ml/200μg
『抗體來源』Rabbit
『克隆類型』polyclonal
『交叉反應(yīng)』Human, Mouse, Rat
『產(chǎn)品類型』一抗
『研究領(lǐng)域』細胞生物 信號轉(zhuǎn)導 G蛋白偶聯(lián)受體 G蛋白信號
『蛋白分子量』predicted molecular weight: 55kDa
『性狀』Lyophilized or Liquid
『免疫原』KLH conjugated synthetic peptide derived from human ARHGAP15
『亞型』IgG
『純化方法』affinity purified by Protein A
『儲存液』Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
『產(chǎn)品應(yīng)用』WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
『保存條件』Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
『產(chǎn)品介紹』Rho GTPases, which play fundamental roles in numerous cellular processes, are initiated by external stimuli that signal though G-protein coupled receptors. ARHGEF15 (Rho guanine nucleotide exchange factor (GEF) 15), also known as ARGEF15 or Vsm-RhoGEF, is a 841 amino acid protein expressed in the vascular smooth muscle of coronary artery. ARHGEF15 functions as a specific guanine nucleotide exchange factor for RhoA and interacts with ephrin-A4 in vascular smooth muscle cells. Containing one DH (DBL-homology) domain, ARHGEF15 is phosphorylated on tyrosine residues upon ephrin-A1 stimulation. The DH domain consists of a region of about 150 amino acids that induces Rho family GTPases to release GDP. This effectively activates the Rho GTPase by allowing GTP binding. ARHGEF15 is eRho GTP酶激活蛋白15抗體供應(yīng) ncoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.
Function : ARHGAP15 is an activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Overexpression results in an increase in actin stress fibers and cell contraction.
Subcellular Location : Cytoplasm. Membrane; Peripheral membrane protein
Similarity : Contains 1 PH domain.
Contains 1 Rho-GAP domain.
Database links : UniProtKB/Swiss-Prot: Q53QZ3.2
E-(Hu)（03）-00869 人抗組蛋白(H2A-H2B)-DNA抗體/抗二聚體-DNA抗體elisa試劑盒 ，英文名： histone H2A-H2B-DNA autoantibody ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00870 人抗雙鏈DNA抗體/天然DNA抗體(dsDNA)elisa試劑盒 ，英文名： anti-double stranded DNA,dsDNA ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00871 人抗核小體抗體IgG(AnuA-IgG)elisa試劑盒 ，英文名： anti-nucleosome antibody IgG,AnuA-IgG ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00872 人抗硬皮病抗體70(SCL70/topoⅠ)elisa試劑盒 ，英文名： anti-scl70 antibody,SCL70/topoⅠELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00873 人抗SS-B/La抗體elisa試劑盒 ，英文名： SS-B/La Antibody,ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00874 人落葉型天皰瘡抗體(PF)elisa試劑盒 ，英文名： Pemphigus Foliaceus,PF ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00875 人β2糖蛋白1抗體IgA(β2-GP1 Ab IgA)elisa試劑盒 ，英文名： β2-Glycoprotein 1 antibody IgA,β2-GP1 Ab IgA ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00876 人β2糖蛋白1抗體IgM(β2-GP1 Ab IgM)elisa試劑盒 ，英文名： β2-Glycoprotein 1 Antibody IgM,β2-GP1 Ab IgM ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00877 人β2糖蛋白1抗體IgG(β2-GP1 Ab IgG)elisa試劑盒 ，英文名： β2-Glycoprotein 1 Antibody IgG,β2-GP1 Ab IgG ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00878 人抗心磷脂抗體IgA(ACA-IgA)elisa試劑盒 ，英文名： anti-cardiolipin antibody IgA,ACA-IgA ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00879 人抗心磷脂抗體IgM(ACA-IgM)elisa試劑盒 ，英文名： anti-cardiolipin antibody IgM,ACA-IgM ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00880 人抗心磷脂抗體IgG(ACA-IgG)elisa試劑盒 ，英文名： anti-cardiolipin antibody IgG,ACA-IgG ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00881 人抗高爾基體抗體(AGAA)elisa試劑盒 ，英文名： anti-golgi appaRatus antibody,AGAA ELISA Kit ，Rho GTP酶激活蛋白15抗體供應(yīng) 規(guī)格： 96T/48T
E-(Hu)（03）-00882 人S100鈣結(jié)合蛋白A9/鈣粒蛋白B(S100A9)elisa試劑盒 ，英文名： S100 calcium binding protein A9/calgranulin B,S100A9 ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00883 人S100鈣結(jié)合蛋白A8/鈣粒蛋白A(S100A8)elisa試劑盒 ，英文名： S100 calcium binding protein A8/calgranulin A,S100A8 ELISA Kit ，規(guī)格： 96T/48T
E-(Hu)（03）-00884 人前病毒整合位點1(Pim1)elisa試劑盒 ，英文名： proviral integRation site 1,Pim1 ELISA Kit ，規(guī)格： 96T/48T
