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聯(lián)系我時,請告知來自 智慧城市網“Anti-EPS15抗體,胞吞調控蛋白Eps15抗體一抗“我公司擁有*的細胞服務技術,*的儀器設備和專業(yè)的ELISA檢測試劑盒、生物索標記、熒光索標記、酶標記等,廣泛用于多種分析研究與技術測定。咨詢,我們將竭誠為你服務!
Anti-EPS15抗體,胞吞調控蛋白Eps15抗體一抗產品介紹:
Elucidation of the mechanism by which receptor tyrosine kinases (RTKs) modulate cellular physiology in response to stimuli is critical to the understanding of growth regulation. Miscues in RTK signaling pathways can result in cellular transformation and ultimay in cancer. Two novel EGF receptor substrates designated EGF-receptor pathway substrates 8 and 15, or Eps8 and Eps15, have been described. Eps8 and Eps15 are proteins, respectively that become tyrosine phosphorylated subsequent to EGF stimulation. Overexpression of Eps15 in NIH/3T3 cells causes cellular transformation, implying involvement in the regulation of cell proliferation. Eps15 is capable of binding the amino terminal portion of Crk via a conserved proline-rich domain, characteristic of all Crk binding proteins (5). Overexpression of Eps8 in both fibroblasts and hematopoietic cells results in an increased mitogenic response to EGF. Eps8 has been shown to associate with the EGF receptor despite its lack of a functional SH2 domain. Further characterization suggests the protein has both a PH domain and a SH3 domain, the functional significance of which are not yet known.
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產品詳情:
產品編號:HRK-11251R
產品規(guī)格: 0.1ml/0.2ml
產品別名:AF 1P; AF 1p protein; AF1P; ALL1 fused gene from chromosome 1; Epidermal growth factor receptor pathway substrate 15; Epidermal growth factor receptor substrate 15; EPS 15; MLLT 5; MLLT5; Protein Eps 15; Protein Eps15; EPS15_HUMAN
產品價格:詢價(電詢或客服)
產品用途:科研實驗
貯 存: 貯存于-20℃.
與“"有關的其他產品:
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Anti-IGF-I 胰島素樣生長因子-I抗體
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