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Anti-CYB5R3抗體,細(xì)胞色素b5還原酶3抗體科研

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聯(lián)系人:韓經(jīng)理 (銷售)

產(chǎn)品簡介

“Anti-CYB5R3抗體,細(xì)胞色素b5還原酶3抗體科研“我公司擁有*的細(xì)胞服務(wù)技術(shù),*的儀器設(shè)備和專業(yè)的ELISA檢測試劑盒、生物索標(biāo)記、熒光索標(biāo)記、酶標(biāo)記等,廣泛用于多種分析研究與技術(shù)測定。咨詢,我們將竭誠為你服務(wù)!

詳細(xì)介紹

Anti-CYB5R3抗體,細(xì)胞色素b5還原酶3抗體科研產(chǎn)品介紹:

CYB5R3 is a 301 amino acid protein encoded by the human gene CYB5R3. CYB5R3 belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and has two naturally occuring isoforms. Isoform 1 is anchored to the cytoplasmic side of the endoplasmic reticulum membrane and mitochondrion outer membrane, while isoform 2 is the soluble form found in erythrocytes. CYB5R3 is involved in the desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism and, in erythrocytes, methemoglobin reduction. A serine residue at position 117 seems to only be found in persons of African origin. The allele frequency is 0.23 in African Americans. It is not found in Caucasians, Asians, Indo-Aryans or Arabs. This difference seems to have no effect on the enzyme activity. Defects in CYB5R3 are the cause of hereditary methemoglobinemia (HM). There are three forms of this disease: type 1 (HM1), in which the enzyme is only deficient in erythrocytes with a mild cyanosis; type 2 (HM2), in which the enzyme is compley deficient; and type 3 (HM3), where the deficiency is seen in all blood cells. Type 2 is a severe form accompanied by mental retardation and neurological impairment. 


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產(chǎn)品詳情:
產(chǎn)品編號:HRK-12162R
產(chǎn)品規(guī)格: 0.1ml/0.2ml
產(chǎn)品別名:B5R; Cyb5r3; Cytochrome b5 reductase 3; Cytochrome b5 reductase; DIA1; Diaphorase 1; Diaphorase-1; NADH cytochrome b5 reductase 3; NADH-cytochrome b5 reductase 3 membrane-bound form; NADH-cytochrome b5 reductase 3 soluble form; NB5R3_HUMAN; OTTHUMP00000028761; OTTHUMP00000198435; OTTHUMP00000198574; OTTHUMP00000198662; OTTHUMP00000198665
產(chǎn)品價(jià)格:詢價(jià)(電詢或客服)
產(chǎn)品用途:科研實(shí)驗(yàn)
貯 存:   貯存于-20℃.

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