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華瑞科研網(wǎng)-ELISA試劑盒
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更新時間:2018-04-18 22:16:40瀏覽次數(shù):267次
聯(lián)系我時,請告知來自 智慧城市網(wǎng)“Anti-BMPR1B抗體,骨形態(tài)發(fā)生蛋白受體1B抗體科研"我公司擁有*的細胞服務技術,*的儀器設備和專業(yè)的ELISA檢測試劑盒、生物索標記、熒光索標記、酶標記等,廣泛用于多種分析研究與技術測定。咨詢,我們將竭誠為你服務!
Anti-BMPR1B抗體,骨形態(tài)發(fā)生蛋白受體1B抗體科研產(chǎn)品介紹:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5.
Involvement in disease; Defects in BMPR1B are the cause of acromesomelic chondrodysplasia with genital anomalies (AMDGA). Acromesomelic chondrodysplasias are rare hereditary skeletal disorders characterized by short stature, very short limbs, and hand/foot malformations. The severity of limb abnormalities increases from proximal to distal with profoundly affected hands and feet showing brachydactyly and/or rudimentary fingers (knob-like fingers).
Defects in BMPR1B are a cause of brachydactyly type A2 (BDA2) [MIM:112600]. Brachydactylies (BDs) are a group of inherited malformations characterized by shortening of the digits due to abnormal development of the phalanges and/or the metacarpals. They have been classified on an anatomic and genetic basis into five groups, A to E, including three subgroups (A1 to A3) that usually manifest as autosomal dominant traits. BDA2 was described first in a large Norwegian kindred. BDA2 is caused by mutations in BMPR1B gene and studies demonstrate that these mutations function as dominant negatives in vitro and in vivo.
與“Anti-BMPR1B抗體,骨形態(tài)發(fā)生蛋白受體1B抗體科研"有關的產(chǎn)品:
人凋亡誘導因子(AIF)試劑盒說明書,96T/48T優(yōu)質(zhì)
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人信號轉(zhuǎn)導分子(Smad1)試劑盒說明書,96T/48T優(yōu)質(zhì)
人信號轉(zhuǎn)導分子7(Smad7)試劑盒說明書,96T/48T優(yōu)質(zhì)
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人血清素/血清胺(ST)試劑盒說明書,96T/48T優(yōu)質(zhì)
產(chǎn)品詳情:
產(chǎn)品編號:HRK-6639R
產(chǎn)品規(guī)格: 0.1ml/0.2ml
產(chǎn)品別名:BMPR-IB; Activin receptor like kinase 6; Acvrlk6; ALK 6; ALK6; alk6tr; BMP type-1B receptor; BMPR IB; BMPR-1B; Bmpr1b; BMPRIB; BMR1B_HUMAN; Bone morphogenetic protein receptor type 1B; Bone morphogenetic protein receptor type IB; Bone morphogenetic protein receptor type-1B; BR 1b; BR1b; CDw 293; CDw293; CDw293 antigen; CFK 43a; CFK43a; Serine/threonine receptor kinase; zALK 6; zALK6
產(chǎn)品價格:詢價(電詢或客服)
產(chǎn)品用途:科研實驗
貯 存: 貯存于-20℃.
與“"有關的其他產(chǎn)品:
Anti-CKⅠα/STK(Casein kinase Ⅰα/Serine/Threonine Protein KinaseⅠα/) 屬絲/*蛋白質(zhì)激酶抗體
Anti-CKⅡα/STK(Casein kinase Ⅱα;Serine/Threonine Protein KinaseⅡα) 屬絲/*蛋白質(zhì)激酶抗體
Anti-CKⅡα/STK(Casein kinase Ⅱα;Serine/Threonine Protein KinaseⅡα) 屬絲/*蛋白質(zhì)激酶抗體
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Anti-CK18(Cytokeratin 18) 細胞角蛋白18抗體
Anti-CK18(Cytokeratin 18)C-term 細胞角蛋白18抗體(C端)
Anti-CK18(Cytokeratin 18) 細胞角蛋白18抗體
Anti-CK14/17/42/10 細胞角蛋白14抗體
Anti-CK15(Cytokeratin 15) 細胞角蛋白15抗體
Anti-CK16(Cytokeratin 16) 細胞角蛋白16抗體
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華瑞科研網(wǎng)-ELISA試劑盒